MedCitizens

StartUPDATES: New Developments for Healthcare Startups

This week, check out news from Alpha Sophia, Encellin, CalmWave, Essential AI, and MATTER.

Alpha Sophia announced an upcoming change to its pricing structure for the Growth Plan, effective from January 1, 2024. To better align with the usage patterns of its valued customers, Alpha Sophia will increase its annual price to $4,800 and include three users by default. The cost for additional users to the platform will remain unchanged at $240 annually. Alpha Sophia is proud to offer a powerful healthcare commercial intelligence software solution at a price that is not prohibitive to small and growing businesses.


Encellin, which has developed an Encapsulated Cell Replacement Therapy (EnCRT) to isolate therapeutic cells from the body’s immune system, to help therapeutic cells survive in the body, has closed a $9.9 million funding round, according to a press release.

The company’s technology was developed in the lab of Dr. Tejal Desai at the University of California in San Francisco, according to Encellin’s website.

Once implanted, cells within the porous EnCRT are able to exchange the biomolecules with the body, which Encellin seeks to demonstrate will provide a therapeutic benefit and function as a living medicine, according to the announcement.

The new funding will advance a Phase 1 clinical trial. First-in-human data from the Phase 1 study is expected next year. The financing will also be used for team expansion and further development of the technology platform.

To learn more, click here.


CalmWave, which uses artificial intelligence to reduce alarm fatigue in hospitals and improve nursing staff retention, is now available in the AWS Marketplace. The curated online software store helps customers find, buy, and use select software and services that run on Amazon Web Services, according to a press release.

“Due to over alarming ICUs, extended work shifts, and understaffing in an already burdened healthcare system, nurses today are grappling with alarm fatigue at unprecedented scale and CalmWave solves this horrible status quo,” said CalmWave CEO and Founder Ophir Ronen. “Availability on the AWS Marketplace streamlines the process for healthcare organizations to adopt the CalmWave solution, empowering them with the technology to eliminate non-actionable alarms in ICUs using their existing, pre-approved AWS budget.”

To learn more, click here.


Essential AI, which seeks to deepen collaborations between computers and humans, has closed a $56.5 million Series A funding round. March Capital led the round with participation from AMD, Franklin Venture Partners, Google, KB Investment, NVIDIA, and Thrive Capital, according to an announcement.

Essential AI previously raised an $8.3 million seed funding round led by Thrive Capital, with participation from investors Amjad Masad, Brad Gerstner, Conviction, Elad Gil, Francis D’Souza, David Patraeus, Gustavo Sapoznik, Jamie Montgomery, and Mei Zuo for a total of nearly $65 million in funding to date.

To read more, click here.


MATTER, a Chicago-based healthcare incubator and innovation hub, seeks applications for the second cohort for its women’s health accelerator 51 Labs. The 2024 program focuses on preventing maternal mortality in the U.S. before, during and after birth and receives support from Health Care Service Corp., Laerdal Million Lives Fund, BayCare, Parkview Health, University of Chicago Medicine, Organon and Stryker, according to a press release.

The maternal mortality rate in the U.S. worsened by 40 percent from 2020 to 2021, according to the Centers for Disease Control and Prevention.

The program includes three tracks: supporting access to regular prenatal care to identify and mitigate potential risk factors earlier; lowering the incidence of maternal health complications; and supporting mothers during the 12 months after giving birth.

To learn more, click here.

Photo: phive2015, Getty Images